Qubit Pharmaceuticals is French-American deeptech startup, focussing on discovering novel small molecule drug candidates for complex disease targets deemed ‘undruggable’. Using our proprietary cutting-edge technologies, we develop our own drug discovery programs that we either co-develop with or license out to pharmaceutical companies. We leverage proprietary molecular simulation and quantum-physics based modeling technology based on over 30 years of research by our academic founders

Qubit Pharma uses a hybrid of classical and quantum computing approach to design more effective and safer drugs, aiming to significantly reduce the time and investment needed to discover new drug candidates. In less than 18 months, Qubit Pharmaceuticals grew its drug discovery portfolio to 6 programs in oncology, inflammation & antivirals leveraging its proprietary platform, Atlas.

Drug discovery through simulation and modeling requires unprecedented computational capabilities beyond the petaflop, or more than one million billion operations per second. Qubit Pharmaceuticals, a deeptech company, has worldwide access to existing and emerging supercomputers with one of the largest private GPU supercomputers for life sciences in France. Our in-house platform Atlas integrates advanced simulation technologies that run on these supercomputers to accelerate calculations by a factor of 100 000, thus performing calculations in a few hours versus over a year's time. These simulations, along with optimized small molecule identification strategies and in-house experts in computational and medicinal chemistry, will allow several chemical series to be explored in parallel.

Qubit Pharmaceuticals is looking for a trainee in RNA Structural Dynamics (M/F) for the RNA platform for Drug Discovery.

RNA is a key regulator of almost every cellular process, and the structures adopted by RNA molecules are central to their functions. It is important to describe the dynamic ensemble of RNA because it reflects the true structural nature of the molecule, and enables describing and predicting key steps in RNA-mediated processes that involve conformational change that cannot be accurately modelled based on static RNA structures. Computer simulations, and in particular atomistic molecular dynamics (MD), allow structural dynamics of biomolecular systems to be investigated with unprecedented temporal and spatial resolution, and are essential to understand and complement experimental investigations of RNA structural dynamics

The perfect fit for this job!

We are looking for talented individuals with a passion for the latest quantum technologies that can bring new ideas to problem solving and desire to apply them to design better drugs, faster.

Your role!

• Molecular dynamics simulations

• Structural dynamics analysis

• Conformational space exploration

• Free energy simulations

Your Qualifications

• Hold a 4-year university degree (either a "Maîtrise", 1st-year Master's (M1), Engineering School diploma, ENS Academic Institution, etc. or equivalent) M2 with a major related to the requested specialization.

• Skills in Chemistry, biochemistry and life sciences - molecular modelling

• Unix usage

• Very good knowledge of written and spoken English

• Good communication skills

The proposal benefits & perks

• Duration: 6 months internship

• Starting date: From february 2025

• Lunch vouchers worth €9 covered at 50%

• Location: Paris 14th arrondissement

For more information about Qubit Pharmaceuticals: www.qubit-pharmaceuticals.com

Join our journey to push the frontiers of science, technology and your career!

“At Qubit Pharma, we don't just dream big—we turn those dreams into real-life innovations in the Drug Discovery world. That's what makes this more than a job - it's a journey where your best ideas can turn into disruptive and game-changing realities."

• Yassine, Atlas Team

“Join Qubit Pharma for a multicultural, multidisciplinary environment that fuels growth. We're a team where diverse perspectives converge, offering scientists and experts like you the opportunity to cultivate expertise and contribute to groundbreaking discoveries."

• Daniele, Research Team

Qubit mission vision and values

A unique career

Qubit Pharmaceuticals is looking for talented professionals to join our team – individuals who have a passion for science, drug discovery and molecular modeling.

Our Vision

Unlock the power of quantum at scale to design better treatments for any target and every patient.

Our Mission

We pioneer quantum-aided drug design and leverage cutting-edge science to design novel molecules for complex targets.

Workplace and culture

We're a diverse mix of expertise, experience and perspectives, united around the passion to make a positive impact in drug design and discovery using the best computational technology.

We’re proud of our inclusive culture where individuals are encouraged to collaborate, lead and grow.

Our Values

We live and work by our values:

• We care genuinely

• We encourage diversity

• We value scientific excellence

• We foster resilience

• We succeed together